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What would happen to theophylline clearance for an asthmatic patient in hospital who could not smoke?
Cigarette smoke causes an increase in levels of CYP1A isozymes. Theophylline is primarily metabolized by the CYP1A system.
What would happen to theophylline clearance for an asthmatic patient in hospital who could not smoke?
A . No change
B . Increase
C . Decrease
Answer: C
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I can’t understand why it decreases. In my opinion the answer should be A.