The use of what hypoglycaemic therapy is acceptable in this situation?

A 25-year-old woman presented at 28 weeks’ gestation after a screening 75-g oral glucose tolerance test, which had shown a fasting plasma glucose of 5.6 mmol/L (3.0C6.0) and a 2-h plasma glucose of 9.8 mmol/L (<7.8). She had a family history of type 2 diabetes mellitus and a pre-pregnancy body mass index of 36 kg/m2 (18C25). Home blood glucose monitoring had shown persistently raised blood glucose despite dietary modification. She refused insulin because of needle phobia and was concerned about drug exposure to her unborn child.

The use of what hypoglycaemic therapy is acceptable in this situation?
A . exenatide
B . glibenclamide
C . gliclazide
D . pioglitazone
E . sitagliptin

View Answer

Answer: B