FPGEE exam

Mechanism of action of isoetharine is:A . Inhibits phosphodiesteraseB . Reduces calcium influx into neuronsC . Potentiates glucose-mediated insulin secretionD . Inhibits phospholipase A2E . beta-2 agonistView AnswerAnswer: E

Indication of Norvir is:A . Streptococcus pneumoniaeB . Cytomegalovirus retinitisC . DiarrheaD . Influenza AE . HIVView AnswerAnswer: E

Route of administration of interferon alpha is:A . IntramuscularB . InhalationC . TopicalD . OralE . Intra-auricularView AnswerAnswer: A

Effect of diltiazem is:A . May increase heart rateB . Decreases triglycerides by 10-20%C . May decrease heart rateD . Inhibits basal gastric acid secretionE . Decreases AV conductionView AnswerAnswer: E

Mechanism of action of vincristine is:A . Inhibits organification of iodine by thyroid glandB . Increases peripheral tissues sensitivity to insulinC . Reduces peripheral insulin resistanceD . Inhibits Na-K-2Cl transporterE . Mitotic spindle poisonView AnswerAnswer: E

Mechanism of resistance of dicloxacillin is:A . Decreased drug uptake by bacteriaB . Mutations in M (matrix) proteinC . Beta-lactamaseD . Penicillin binding proteins (PBPs)E . Antibodies resulting from streptococcal infectionView AnswerAnswer: D

Lansoprazole is not used in which of the following cases?A . GastritisB . Peptic UlcersC . Zollinger-Ellison syndromeD . Thalamus hypertrophyView AnswerAnswer: D

Interactions with other drugs of clonazepam is:A . Lactose: increases absorptionB . meperidineC . Tricyclic antidepressants: potentiate sedationD . cis-platinum - augments nephrotoxicityE . Oral contraceptives: inhibit metabolismView AnswerAnswer: E

Class of nitrogen mustard is:A . AquareticsB . Alkylating agentsC . Lipid lowering drugsD . Drugs affecting calcium homeostasisE . AntiviralsView AnswerAnswer: B

Indication of PTU is:A . GlaucomaB . Migraine prophylaxisC . Thyrotoxicosis - preparation for radioactive iodine therapyD . Severe recurrent ventricular tachyarrhythmiasE . Broad spectrum antibacterial agentView AnswerAnswer: C