FPGEE exam

Bioavailability is related to which of the following parameters, according to the equation F = 1 - EA . ExcretionB . EliminationC . Extraction RatioD . Enterohepatic RecyclingView AnswerAnswer: C

Which of the following enzymes could directly act on codeine?A . Glucuronyl transferaseB . SulfotransferaseC . Glutathione transferaseD . A & BE . All of the aboveView AnswerAnswer: D

Effect of bisacodyl is:A . Decreases total cholesterol by 8-12%B . Decreases water absorptionC . Decreases total cholesterol by 20-50%D . Enhances mucociliary clearanceE . Decreases triglycerides by 10-20%View AnswerAnswer: B

Route of administration of methadone is:A . SubcutaneousB . InhalationC . IntrathecalD . OralE . TransdermalView AnswerAnswer: D

Which of the following statements refers to HPMPC?A . Tricyclic.B . Cytosine monophosphate analogC . Works by accumulating in and changing pH of lysosomes.D . Mild intrinsic sympathomimetic activity - does not decrease heart rate and contractility as much during exercise.E . Metabolized in liver by P450.View AnswerAnswer: B

Mechanism of action of amiloride is:A . Inhibits dihydrofolate reductaseB . Modulation of CD3 receptor from the cell surfaceC . Inhibits renal epithelial Na channelsD . Aldosterone antagonistE . Inhibits DNA-dependent RNA polymeraseView AnswerAnswer: C

Class of famciclovir is:A . NSAIDB . AntidepressantsC . Autonomic nervous system drugsD . AntiviralsE . Oral hypoglycemicsView AnswerAnswer: D

Which of the following statements refers to bretylium?A . May induce mild hypotension and worsen congestive heart failure in some patients. However, most CHF patients can tolerate it.B . Duration of action is usually several days.C . Has been show to be more effective than six other agents in preventing...

Which of the following drugs is associated with the reaction of extreme photosensitivity?A . DigitalisB . NiacinC . TetracyclineD . FluoroquinolonesView AnswerAnswer: C

Which of the following drugs is associated with the reaction of hepatitis?A . Valproic acidB . QuinidineC . IsoniazidD . EthosuximideView AnswerAnswer: C