FPGEE exam

Indication of ticarcillin is:A . Streptococcus pneumoniaeB . Varicella zoster virusC . Myocardial infarctionD . Generalized motor seizuresE . Bone marrow failure states (aplastic anemia, myelodysplasias) (investigational)View AnswerAnswer: A

Side effect of clindamycin is:A . Colitis (by Chlostridium difficili)B . MalabsorptionC . ConstipationD . HypoglycemiaE . HepatotoxicityView AnswerAnswer: A

Route of administration of ofloxacin is:A . Intra-auricularB . SublingualC . OralD . IVE . IntramuscularView AnswerAnswer: C

Which of the following Cytochrome P450 isozymes is responsible for the bulk of phase I metabolism?A . CYP1A2B . CYP2C9C . CYP2D6D . CYP3A4E . CYP51View AnswerAnswer: E

Which of the following causes the smallest change in solubility?A . HydroxylationB . GlucuronidationC . SulfationD . Glutathione conjugationView AnswerAnswer: A

For the majority of drugs, which of the following equations correctly defines clearance?A . Cl = Elimination rate/CpB . Cl = QxEC . Cl = .7VD/t1/2D . All are correctView AnswerAnswer: D

Side effect of dipyridamole is:A . DiarrheaB . HeadacheC . BleedingD . HypercalcemiaE . Pseudothrombocytopenia (clumping of platelets)View AnswerAnswer: B

Site of metabolism of zolpidem is:A . LiverB . NoneC . Reticuloendothelial systemD . LeukocytesE . UnknownView AnswerAnswer: A

Which of the following is considered a class IA Sodium Channel blocker?A . MexiletineB . AminodaroneC . QuinidineD . ProcainamideView AnswerAnswer: B

Potassium sparing diuretics have the primary effect upon the _____ found in the kidney.A . Proximal convoluted tubuleB . Loop of HenleC . Collecting ductD . Distal convoluted tubuleView AnswerAnswer: D