Which drug is most likely to be responsible for his diabetes of new onset?

A 55-year-old man with mild polyuria and tiredness was seen on a renal ward. He had had a living-related kidney transplant 6 months previously. He had good graft function while being treated with prednisolone 5 mg daily, mycophenolate mofetil 1 g twice daily and tacrolimus 3 mg twice daily. He was also taking atenolol 50 mg daily and simvastatin 40 mg daily.

Investigations:

haemoglobin A1c75 mmol/mol (20C42)

random plasma glucose18.0 mmol/L

Which drug is most likely to be responsible for his diabetes of new onset?
A . atenolol
B . mycophenolate mofetil
C . prednisolone
D . simvastatin
E . tacrolimus

View Answer

Answer: E